Mathew Tait returns at full-back, and there are starting places for Scott Hamilton, Matt Smith and Dan Bowden in the backline, with Toby Flood and Ben Youngs at half-back.
Warriors expect to welcome their biggest crowd of the season so far for Friday's fixture as they defend an unbeaten home record stretching back to September.
Leicester Tigers (v Worcester Warriors, Sixways, Friday 8pm)
15 Mathew Tait
14 Scott Hamilton
13 Matt Smith
12 Dan Bowden
11 Adam Thompstone
10 Toby Flood
9 Ben Youngs
1 Logovi'i Mulipola
2 Rob Hawkins
3 Martin Castrogiovanni
4 Louis Deacon (c)
5 Ed Slater
6 Tom Croft
7 Steve Mafi
8 Thomas Waldrom
Replacements
16 George Chuter
17 Marcos Ayerza
18 Dan Cole
19 Graham Kitchener
20 Julian Salvi
21 Micky Young
22 Anthony Allen
23 Niall Morris