Up front, Adam Eustace is selected to partner Alex Brown in the second row whilst Akapusi Qera features for the first time since the home victory over Newcastle on December 5th.
Amongst the replacements, there is one new face and one not so new face!
Welsh international scrum half Andy Williams, currently on loan from Moseley with Jordi Pasqualin having temporarily moved in the opposite direction to Billesley Common, is named in the Gloucester matchday squad for the first time.
Meanwhile, hooker Olivier Azam is back for potentially his first appearance since his try scoring contribution at Headingley against Leeds on October 4th.
Ahead of his team announcement, Redpath was pulling no punches when it came to assessing the importance of Saturday's fixture: "Worcester have beaten us I think on the last three occasions, twice away and once at home.
"Everyone must understand the importance of this game. A win would take us up two places and a defeat would move us down one place. We're only seven points off the bottom and four points off sixth.
"So, these next two games are massive. Our supporters will come on Saturday and sing their hearts out and they'll want people to perform. But we have to be clinical.
"I think over 90 points of their 140 odd have come from the boot of Willie Walker so what is going to be important is discipline. If our discipline is poor then it won't be a game because Willie will kick the points."
Gloucester Rugby: Olly Morgan; Charlie Sharples, James Simpson-Daniel, Eliota Fuimaono-Sapolu, Lesley Vainikolo; Nicky Robinson, Dave Lewis; Nick Wood, Scott Lawson, Greg Somerville; Adam Eustace, Alex Brown; Alasdair Strokosch, Akapusi Qera, Gareth Delve (capt)
Replacements: Olivier Azam, Alasdair Dickinson, Pierre Capdevielle, Dave Attwood, Luke Narraway, Andy Williams, Carlos Spencer, Tim Molenaar